Formulation and Evaluation of Floating Tablets of Ranitidine Hydrochloride with Liquorice as Natural Ulcer Protective Agent
نویسندگان
چکیده
منابع مشابه
Formulation and evaluation of effervescent floating tablets of tizanidine hydrochloride.
Tizanidine hydrochloride is an orally administered prokinetic agent that facilitates or restores motility through-out the length of the gastrointestinal tract. The objective of the present investigation was to develop effervescent floating matrix tablets of tizanidine hydrochloride for prolongation of gastric residence time in order to overcome its low bioavailability (34-40 %) and short biolog...
متن کاملFormulation and in vitro evaluation of floating tablets of hydroxypropyl methylcellulose and polyethylene oxide using ranitidine hydrochloride as a model drug
The present study was carried out with an objective of preparation and in vitro evaluation of floating tablets of hydroxypropyl methyl cellulose (HPMC) and polyethylene oxide (PEO) using ranitidine hydrochloride as a model drug. The floating tablets were based on effervescent approach using sodium bicarbonate a gas generating agent. The tablets were prepared by dry granulation method. The effec...
متن کاملFormulation, characterization and physicochemical evaluation of ranitidine effervescent tablets.
PURPOSE The aim of this study was to design, formulate and physicochemically evaluate effervescent ranitidine hydrochloride (HCl) tablets since they are easily administered while the elderly and children sometimes have difficulties in swallowing oral dosage forms. METHODS Effervescent ranitidine HCl tablets were prepared in a dosage of 300 mg by fusion and direct compression methods. The powd...
متن کاملFloating tablets of hydralazine hydrochloride: optimization and evaluation
Hydralazine hydrochloride has a half-life of 2 to 4 hours with an oral bioavailability of 26-50%. Since hydralazine has a demethylating effect on various suppressor genes, it can be used in various types of cancer to support chemotherapy. The purpose of this study was to optimize and evaluate floating tablets of hydralazine hydrochloride designed to prolong the gastric residence time and to pro...
متن کاملFormulation and Evaluation of Taste Masked Mouth Dissolving Tablets of Levocetirizine Hydrochloride
Aim of this research work was to develop mouth dissolving tablet that disintegrates rapidly in mouth by using tasteless complex of Levocetirizine and Tulsion-335. Effect of different parameters such as swelling time, resin activation, drug resin ratio as well as stirring time was optimized by taste and percentage drug loading. Formulated DRC (Drug Resin Complex) was characterized by infrared...
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ژورنال
عنوان ژورنال: International Journal of Pharmacy and Pharmaceutical Research
سال: 2019
ISSN: 2349-7203
DOI: 10.25166/ijppr.2020.v17i01.04